Agenda: Patient Enrollment Innovative Trends Using a Liquid Biopsy

Wednesday February 9, 2022 | 12.30pm – 3.30pm PT | 3.30pm – 6.30pm ET

12:30 pm Hanson Wade & Guardant Health Opening Remarks

Clinical Trends Using MRD in Bladder, Lung & Breast

Synopsis

The objective of this session is to review and discuss the latest trends in Bladder, Lung and Breast oncology trials and innovative MRD use cases to solve outstanding clinical challenges in early-stage disease. Our expert speaker and panelists will discuss unmet clinical and diagnostic needs in the adjuvant and neoadjuvant settings, as well as the potential of LBx to provide a solution.

12:35 pm Presentation

  • David Gandara Director, Thoracic Oncology, UC Davis Comprehensive Cancer Center

1:00 pm Panel Discussion

  • David Gandara Director, Thoracic Oncology, UC Davis Comprehensive Cancer Center
  • Pedram Razavi Medical Oncologist, Memorial Sloan Kettering Cancer Center
  • Thereasa Rich Medical Science Liaison, Guardant Health
  • Petros Grivas Director of Colon Cancer Research, Weill Cornell Medicine

Guardant Health Clinical Roll-out of MRD Monitoring

1:35 pm Presentation

2:00 pm Break

Copy Number Alterations: Clinical Unmet Needs & LBx Impact

Synopsis

This session will delve into the specific challenges that late-stage cancer patients are facing with emerging copy number alterations and in the innovative diagnostic solutions to inform clinical decisions. For instance, our panel will discuss mechanisms of resistance (e.g. CCNE1, ERBB2, MET) as well as the corresponding biomarkerinformed treatments. The panelists will also touch on the underlying technological (focal amplification vs. aneuploidy) and clinical challenges for a prospective trial roll-out and LBx considerations.

2:05 pm Presentation

  • David Chun Cheong Tsui Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus

2:30 pm Presentation

  • Yoshiaki Nakamura Department of Gastroenterology & Gastrointestinal Oncology, National Cancer Center Hospital East

2:55 pm Panel Discussion

  • David Chun Cheong Tsui Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus
  • Yoshiaki Nakamura Department of Gastroenterology & Gastrointestinal Oncology, National Cancer Center Hospital East
  • Justin Odegaard Vice President, Clinical Development, Guardant Health
  • Sara Wienke Medical Science Liaison, Guardant Health

3:25 pm Closing Remarks

3:30 pm End of Guardant Health Workshop